Handling large datasets in Google Sheets requires a structured approach to ensure data accuracy and efficiency. I typically start by organizing the data using filters and pivot tables, which help in sorting and summarizing the information effectively. For data accuracy, I rely on formulas like VLOOKUP and SUMIF to cross-reference and validate data entries. Additionally, I use the QUERY function and array formulas to perform more complex data manipulations and analyses. To identify patterns and trends, I create visual representations using charts and dashboards, which provide a clear overview of the data insights. Throughout this process, I maintain a focus on data integrity by regularly checking for errors and inconsistencies, ensuring that the final analysis is both accurate and actionable.